This Journal feature begins with a case vignette highlighting a rare clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Chronic fatigue syndrome affects people differently, and its symptoms can be widespread. Muscle pain, digestive issues and flu-like symptoms are a few of the less obvious signs of the condition. It’s ...

Chronic pelvic pain syndrome (CPPS) and prostatitis represent a complex spectrum of disorders characterised by persistent discomfort, inflammation and urinary dysfunction. While they may share ...

Another chronic condition called chronic fatigue syndrome (CFS), or myalgic encephalomyelitis, comprises a complex multisystem disease that is typically characterized by severe fatigue. 2 Both these ...

Almost everyone has pain sometimes. It might start as a twinge in your back, a dull ache in your knee, a tingling on the bottoms of your feet. Maybe you slept funny, or hoisted a full bag of groceries ...

Post-vasectomy pain syndrome (PVPS) is a complication of a vasectomy where you experience long-term testicular pain. It’s often treatable with medications, but some people need surgery. A vasectomy is ...

I’m often asked, “What does a typical patient in the Pain Recovery Program look like?” There is no simple answer to that complex question. Chronic pain syndrome, classified as pain that persists more ...

Fatigue can stem from a variety of illnesses and life stressors, but when that exhaustion lasts for months — often following an infection — it may indicate a condition called chronic fatigue syndrome.

Elise Kozal spent the better part of her college years with a burning bladder and urethra—a sensation that would send her to the bathroom constantly only to feel, frustratingly, as if she could never ...