Fetal exposure to excess glucocorticoids (GCs) may be a critical link between an adverse fetal environment and programming of CV disease and hypertension. Experimental studies demonstrate that excess ...

The placenta serves as the central regulator of nutrient, gas and waste exchange between mother and fetus while also acting as an endocrine organ that adapts to maternal environment. Placental ...

When new ideas arise in the sciences, it often takes time for the ideas to meander into public awareness. Such is the case with the idea of "fetal programming"—an idea that first became prominent in ...

Adverse in-utero insults during fetal life alters offspring’s developmental trajectory, including that of the cardiovascular system. Gestational hyperandrogenism is once such adverse in-utero insult.

A mother’s intake from the prenatal through postnatal periods influences programming of the growth and development of her child. The mechanisms by which this takes place involve a complex interplay of ...

Epidemiological studies have suggested that size at birth contributes to increased cardiovascular disease (CVD) risk in later life. Findings from experimental studies are providing insight into the ...