From benign growth to pancreatic cancer: New study shows how the switch gets flipped

As we age, our cells accumulate genetic changes—mutations—some of which open the door to cancer. Scientists call these ...
Pancreatic Cancer Action Network

First RAS Inhibitor Extends Survival in Previously Treated Metastatic Pancreatic Adenocarcinoma: What You Need to Know

Revolution Medicines shared Phase III clinical trial results for a pill called daraxonrasib in patients with previously ...
Neuroscience News

Somatic Evolution Revealed as a Primary Driver of Autoimmune Disease

What causes autoimmune disease? A new study finds that somatic mutations in immune checkpoint genes like PDL1 trigger the ...
mskcc.org

There’s an App for That: When the Meaning of a BRCA Mutation Isn’t Clear-Cut

A new database and mobile app called BRCA Exchange is making it easier for experts to share information about cancer-related gene mutations. Summary Clinical genetics experts from MSK and other ...
CURE

Rezatapopt Shows Activity in Pretreated Ovarian Cancer With TP53 Mutation

PYNNACLE enrolled heavily pretreated TP53 Y220C–mutant ovarian cancer (median four prior lines), including platinum-resistant ...