Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a hereditary small vessel disease primarily caused by mutations in the NOTCH3 gene. These ...
Jacob Haendel, 32, has been recovering from both acute toxic progressive leukoencephalopathy (TAPL) and locked-in syndrome since 2018, documenting the process online. In 2017, Haendel was diagnosed ...
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