Chinese scientists have uncovered two major genes responsible for sorghum's double-grain spikelet that dramatically enhance grain number and crop yield. A substantial 35.7-kilobase intrachromosomal ...
Comparative study of tools for copy number variation detection using next-generation sequencing data
Copy number variation (CNV) plays an important role in disease susceptibility as a type of intermediate-scale structural variation (SV). Accurate CNV detection is crucial for understanding human ...
Single-molecule localization microscopy (SMLM) is used to image biological samples at resolutions below the diffraction limit 1,2. The resolution of SMLM is limited by the density of labeling and ...
Complex engineering of human cell lines reveals genome's unexpected resilience to structural changes
The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.
The first and largest dataset of genomic structure variations specific to childhood cancers was published today by scientists from St. Jude Children's Research Hospital and the National Cancer ...
Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...
As buildings age, the demand for effective monitoring of their structural integrity has grown significantly. A breakthrough in nano-optical sensor technology now enables precise, real-time measurement ...
A substantial chromosomal inversion in the DG1 promoter upregulates its expression. It gives rise to a double-grain spikelet trait remarkably augmenting the grain number and yield in sorghum and ...
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